Tremfya: First Fully Under-the-Skin IL-23 Inhibitor Shot Approved for Ulcerative Colitis and Crohn’s Disease

Tremfya (guselkumab) is a lab-made, dual-acting antibody medication that reduces inflammation by targeting the interleukin-23 (IL-23) protein and blocking a majority of the cells that produce it. It is available by prescription. The FDA has… Read more

FDA Approves Enbumyst: First and Only Nasal Spray Diuretic for Edema From Heart, Liver, and Kidney Diseases

Enbumyst is a new nasal spray form of bumetanide (first approved by the FDA in 1983). It is a type of medicine called a loop diuretic (also known as a “water pill”), which helps your… Read more

Inluriyo: FDA Approves New Once-Daily Pill for ESR1-Mutated Advanced Breast Cancer in Patients Previously on Hormone Therapy

Inluriyo (imlunestrant) is a new oral treatment for certain types of locally advanced or metastatic breast cancer that has progressed after at least one round of hormone therapy. The FDA has approved it for people whose… Read more

Kygevvi: FDA Approves First Oral Treatment for Thymidine Kinase 2 Deficiency (TK2d)

Kygevvi is a new oral medicine for people with thymidine kinase 2 deficiency (TK2d), an extremely rare genetic condition affecting the muscles. The FDA has approved it for the treatment of adults and children with… Read more

Darzalex Faspro: A New Treatment for High-Risk Smoldering Multiple Myeloma

Darzalex Faspro is a medicine used to treat adults with multiple myeloma, a type of blood cancer, and amyloidosis, a rare condition where abnormal proteins build up in organs. It’s also the first treatment approved… Read more

Caplyta: A New Add-On Option for Adults With Depression

Caplyta (lumateperone) is a once-daily oral medicine now approved to be used with antidepressants to treat major depressive disorder (MDD) in adults. It belongs to a group of medicines called atypical antipsychotics. While experts don’t… Read more

FDA Approves Combined Use of Zepzelca and Atezolizumab as First-Line Maintenance Treatment for Advanced Small-Cell Lung Cancer

Zepzelca (lurbinectedin) is a chemotherapy medicine that damages the DNA of cancer cells by disrupting their protein function and ability to repair DNA. This action makes it difficult for cancer cells to grow, survive, and… Read more

Linzess: First Drug Approved for Children and Adolescents With IBS-C

Linzess (linaclotide) is a prescription medicine that helps ease constipation caused by irritable bowel syndrome (IBS-C). It works by drawing more fluid into your intestines, which makes it easier for stool to pass. The FDA… Read more

FDA Approves Revuforj as a Targeted Oral Therapy for Relapsed or Refractory NPM1-Mutated Acute Myeloid Leukemia

Revuforj (revumenib) is an oral medicine approved for treating a type of cancer called acute myeloid leukemia (AML) that affects your bone marrow and blood. In 2024, Revuforj became the first approved medicine for treating… Read more

Rhapsido: A New Oral Option for Chronic Spontaneous Urticaria

Rhapsido (remibrutinib) is a new oral medicine approved to treat adults with chronic spontaneous urticaria (CSU). CSU is a long-term skin condition that causes itchy hives or swelling without a clear cause. It can last… Read more